C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000099078 Arfgef2-001 ENSMUSG00000074582 10090 + 2:166805588-166898052 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000099078
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000099078 6.485±2.50 12.905±3.40 4.832±0.09 2.714±0.45 7.634±1.80 10.605±2.32 4.903±1.54 9.258±1.39 6.554±2.52 8.932±3.04 2.053±1.22 4.916±1.94 7.397±4.19 10.302±0.49

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XQ CIL_0001XQ_0002 CGP 2:166805588-166946389

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0001881 ISS receptor recycling
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005086 ISS ARF guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005802 ISS trans-Golgi network
GO:0005815 ISS microtubule organizing center
GO:0005829 IEA cytosol
GO:0005879 ISS axonemal microtubule
GO:0006887 IEA exocytosis
GO:0006893 ISS Golgi to plasma membrane transport
GO:0007032 ISS endosome organization
GO:0010256 ISS endomembrane system organization
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016192 IBA vesicle-mediated transport
GO:0017022 IEA myosin binding
GO:0030054 IEA cell junction
GO:0031410 ISS cytoplasmic vesicle
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0032279 ISS asymmetric synapse
GO:0032280 ISS symmetric synapse
GO:0032760 ISS positive regulation of tumor necrosis factor production
GO:0034237 ISS protein kinase A regulatory subunit binding
GO:0035556 IEA intracellular signal transduction
GO:0043197 ISS dendritic spine
GO:0043547 IEA positive regulation of GTPase activity
GO:0050811 ISS GABA receptor binding
GO:0055037 ISS recycling endosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000140866 arfgef2-001 protein_coding Danio_rerio 0 2361
ENSDART00000111852 arfgef2-201 protein_coding Danio_rerio 0 2333
ENST00000371917 ARFGEF2-001 protein_coding Homo_sapiens 0 6530
ENST00000493140 ARFGEF2-002 processed_transcript Homo_sapiens 0 241

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