C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 12b
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102796 Il12b-001 ENSMUSG00000004296 10090 + 11:44400063-44414033 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000102796
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000102796 0.131±0.11 0.040±0.00 0.020±0.00 0.537±0.13 0.171±0.00 0.017±0.00 0.062±0.02 0.015±0.01 0.123±0.06 0.082±0.04 0.016±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008O4 CIL_0008O4_0002 VISTA 11:44325594-44926697
CIL_0008X2 CIL_0008X2_0002 VISTA 11:44334332-44935609
CIL_00087L CIL_00087L_0002 VISTA 11:44356475-44957869
CIL_0005EZ CIL_0005EZ_0002 CGP 11:44400063-44470498

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001916 IDA positive regulation of T cell mediated cytotoxicity
GO:0002230 IDA positive regulation of defense response to virus by host
GO:0002827 IDA positive regulation of T-helper 1 type immune response
GO:0002862 IMP negative regulation of inflammatory response to antigenic stimulus
GO:0004896 IEA cytokine receptor activity
GO:0005125 IDA cytokine activity
GO:0005126 IPI cytokine receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0007166 IDA cell surface receptor signaling pathway
GO:0016020 IEA membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030101 ISS natural killer cell activation
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042093 ISS T-helper cell differentiation
GO:0042102 IDA positive regulation of T cell proliferation
GO:0042104 ISS positive regulation of activated T cell proliferation
GO:0042164 IPI interleukin-12 alpha subunit binding
GO:0042803 IDA protein homodimerization activity
GO:0042832 IGI defense response to protozoan
GO:0043514 IDA interleukin-12 complex
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0051607 IDA defense response to virus
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071346 IDA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000231228 IL12B-001 protein_coding Homo_sapiens 0 508

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