C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CD3 antigen, epsilon polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102832 Cd3e-001 ENSMUSG00000032093 10090 - 9:44998743-45009590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102832
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102832 0.403±0.15 0.210±0.11 0.281±0.03 0.020±0.00 12.917±4.95 0.836±0.16 0.298±0.23 0.683±0.52 0.281±0.16 1.893±0.25 0.312±0.29 0.282±0.18 0.096±0.08 0.100±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0002 VISTA 9:44577224-45180192

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0002669 IDA positive regulation of T cell anergy
GO:0004871 IDA signal transducer activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007584 IEA response to nutrient
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0017124 IEA SH3 domain binding
GO:0031295 IGI T cell costimulation
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032753 IDA positive regulation of interleukin-4 production
GO:0033077 IEA T cell differentiation in thymus
GO:0042101 IEA T cell receptor complex
GO:0042102 IDA positive regulation of T cell proliferation
GO:0042105 IDA alpha-beta T cell receptor complex
GO:0045060 IDA negative thymic T cell selection
GO:0045086 IDA positive regulation of interleukin-2 biosynthetic process
GO:0045879 IDA negative regulation of smoothened signaling pathway
GO:0046641 IDA positive regulation of alpha-beta T cell proliferation
GO:0046649 IMP lymphocyte activation
GO:0046982 IEA protein heterodimerization activity
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 IDA positive regulation of calcium-mediated signaling
GO:0050852 IDA T cell receptor signaling pathway
GO:0050870 IDA positive regulation of T cell activation
GO:0097190 IDA apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000361763 CD3E-001 protein_coding Homo_sapiens 0 302
ENST00000526146 CD3E-004 retained_intron Homo_sapiens 0 298
ENST00000528600 CD3E-007 protein_coding Homo_sapiens 0 302
ENST00000531913 CD3E-009 retained_intron Homo_sapiens 0 302

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