C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: CD3e molecule, epsilon (CD3-TCR complex)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361763 CD3E-001 ENSG00000198851 9606 + 11:118304545-118316175 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000361763
Transcript ID Adipose Adrenal Bladder Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000361763 0.862±0.00 10.302±0.00 0.244±0.00 1.318±0.00 0.076±0.00 0.517±0.00 0.447±0.00 3.641±1.56 1.267±0.27 1.342±0.33 0.168±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0001 VISTA 11:118137591-118740525

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IEA immunological synapse
GO:0002669 IEA positive regulation of T cell anergy
GO:0004871 IEA signal transducer activity
GO:0004888 NAS:IEA transmembrane signaling receptor activity
GO:0005057 TAS receptor signaling protein activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006461 NAS protein complex assembly
GO:0007166 NAS:IEA cell surface receptor signaling pathway
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007172 TAS signal complex assembly
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007584 IEA response to nutrient
GO:0009897 IDA external side of plasma membrane
GO:0016020 IEA membrane
GO:0017124 IPI SH3 domain binding
GO:0019901 NAS protein kinase binding
GO:0030159 NAS receptor signaling complex scaffold activity
GO:0031295 TAS T cell costimulation
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0032753 IEA positive regulation of interleukin-4 production
GO:0033077 IEA T cell differentiation in thymus
GO:0035556 TAS intracellular signal transduction
GO:0042101 IDA T cell receptor complex
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042105 IEA alpha-beta T cell receptor complex
GO:0042110 NAS T cell activation
GO:0042608 NAS T cell receptor binding
GO:0042981 NAS regulation of apoptotic process
GO:0045060 IEA negative thymic T cell selection
GO:0045086 IEA positive regulation of interleukin-2 biosynthetic process
GO:0045879 IEA negative regulation of smoothened signaling pathway
GO:0046641 IEA positive regulation of alpha-beta T cell proliferation
GO:0046649 IEA lymphocyte activation
GO:0046982 IPI protein heterodimerization activity
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050776 TAS regulation of immune response
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IEA positive regulation of T cell activation
GO:0097190 IEA apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102832 Cd3e-001 protein_coding Mus_musculus 0 302

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