C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myocyte enhancer factor 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107476 Mef2a-004 ENSMUSG00000030557 10090 - 7:67231918-67372858 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000107476
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000107476 13.467±6.80 13.988±1.18 4.516±0.51 3.643±0.96 10.094±3.04 7.793±1.65 9.100±2.45 5.715±2.48 2.767±1.40 26.186±2.31 19.123±5.95 3.137±1.14 3.414±1.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000002 IMP mitochondrial genome maintenance
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000165 ISS MAPK cascade
GO:0000790 IDA nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:IC RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC:IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007399 IEA nervous system development
GO:0019901 IPI protein kinase binding
GO:0033613 IPI activating transcription factor binding
GO:0035035 ISS histone acetyltransferase binding
GO:0042826 ISS histone deacetylase binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI:IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 ISS SMAD binding
GO:0048311 IMP mitochondrion distribution
GO:0055005 IMP ventricular cardiac myofibril assembly
GO:0061337 IMP cardiac conduction
GO:0070375 ISS ERK5 cascade
GO:0071277 ISS cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000338042 MEF2A-201 protein_coding Homo_sapiens 0 5171
ENST00000354410 MEF2A-001 protein_coding Homo_sapiens 0 4839
ENST00000449277 MEF2A-004 protein_coding Homo_sapiens 0 4708
ENST00000557785 MEF2A-002 protein_coding Homo_sapiens 0 3461
ENST00000557942 MEF2A-005 protein_coding Homo_sapiens 0 5072
ENST00000558049 MEF2A-010 protein_coding Homo_sapiens 3e-31 139
ENST00000558812 MEF2A-003 protein_coding Homo_sapiens 0 2222
ENST00000558856 MEF2A-011 processed_transcript Homo_sapiens 0 217
ENST00000558983 MEF2A-012 retained_intron Homo_sapiens 0 704
ENST00000559036 MEF2A-006 retained_intron Homo_sapiens 0 466
ENST00000559903 MEF2A-009 protein_coding Homo_sapiens 0 436
ENST00000560493 MEF2A-008 protein_coding Homo_sapiens 0 460
ENST00000561125 MEF2A-007 retained_intron Homo_sapiens 0 776

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