C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: triggering receptor expressed on myeloid cells 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000113237 Trem2-002 ENSMUSG00000023992 10090 + 17:48346488-48352273 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000113237
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000113237 3.116±0.33 0.953±0.26 0.625±0.05 1.674±1.12 1.037±0.34 0.735±0.31 0.373±0.00 0.271±0.12 0.415±0.24 0.889±0.18 0.228±0.11 2.548±1.14 0.742±0.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008F3 CIL_0008F3_0002 VISTA 17:47757242-48358147

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001530 IDA lipopolysaccharide binding
GO:0002588 IEA positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0004888 ISS transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005886 IEA plasma membrane
GO:0016021 IEA integral component of membrane
GO:0031663 IC lipopolysaccharide-mediated signaling pathway
GO:0032497 IDA detection of lipopolysaccharide
GO:0032499 IDA detection of peptidoglycan
GO:0042834 IDA peptidoglycan binding
GO:0045087 IC innate immune response
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0070392 IDA detection of lipoteichoic acid
GO:0070891 IDA lipoteichoic acid binding
GO:0071223 IDA cellular response to lipoteichoic acid
GO:0071224 IDA cellular response to peptidoglycan
GO:0097028 IEA dendritic cell differentiation
GO:0097110 IEA scaffold protein binding
GO:1903078 IEA positive regulation of protein localization to plasma membrane
GO:1903082 IEA positive regulation of C-C chemokine receptor CCR7 signaling pathway
GO:2000350 IEA positive regulation of CD40 signaling pathway

Homologs

No Homologs available.

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