C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific methyltransferase 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114689 Kmt2a-001 ENSMUSG00000002028 10090 - 9:44803355-44881296 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonKidneyLiverLungMuscleOvaryENSMUST00000114689
Transcript ID Adipose Adrenal Breast Colon Kidney Liver Lung Muscle Ovary
ENSMUST00000114689 0.504±0.00 0.990±0.00 1.101±0.00 1.222±0.00 0.449±0.00 0.544±0.22 1.132±0.03 0.709±0.13 1.874±1.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0002 VISTA 9:44577224-45180192

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006306 IMP DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0008270 ISS zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0035097 ISS histone methyltransferase complex
GO:0035162 IMP embryonic hemopoiesis
GO:0042800 ISS histone methyltransferase activity (H3-K4 specific)
GO:0043984 ISS histone H4-K16 acetylation
GO:0045322 ISS unmethylated CpG binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0051568 ISS histone H3-K4 methylation
GO:0051569 IMP regulation of histone H3-K4 methylation
GO:0070577 ISS lysine-acetylated histone binding
GO:0071339 ISS MLL1 complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000104525 kmt2a-201 protein_coding Danio_rerio 0 824
ENSDART00000148840 kmt2a-001 protein_coding Danio_rerio 0 824
ENST00000389506 KMT2A-015 protein_coding Homo_sapiens 0 15520
ENST00000392873 KMT2A-017 protein_coding Homo_sapiens 0 750
ENST00000420751 KMT2A-004 processed_transcript Homo_sapiens 5e-40 167
ENST00000525408 KMT2A-014 retained_intron Homo_sapiens 0 1116
ENST00000527839 KMT2A-013 retained_intron Homo_sapiens 0 667
ENST00000527869 KMT2A-016 protein_coding Homo_sapiens 0 322
ENST00000528278 KMT2A-005 retained_intron Homo_sapiens 0 1166
ENST00000529852 KMT2A-006 protein_coding Homo_sapiens 0 357
ENST00000531904 KMT2A-002 protein_coding Homo_sapiens 0 4927
ENST00000532204 KMT2A-010 protein_coding Homo_sapiens 0 357
ENST00000533790 KMT2A-007 protein_coding Homo_sapiens 0 817
ENST00000534085 KMT2A-009 retained_intron Homo_sapiens 3e-28 128
ENST00000534358 KMT2A-001 protein_coding Homo_sapiens 0 15610

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