C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cystathionase (cystathionine gamma-lyase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000118539 Cth-001 ENSMUSG00000028179 10090 - 3:157894248-157925077 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000118539
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000118539 7.401±1.25 6.058±0.37 2.072±0.61 1.083±0.50 4.184±0.62 21.847±2.88 0.619±0.18 93.224±15.63 193.405±160.97 2.727±0.33 0.974±0.31 2.303±0.67 1.627±0.73 0.724±0.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000WV CIL_0000WV_0002 CGP 3:157566892-157925077

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004123 ISS cystathionine gamma-lyase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0018272 ISS protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
GO:0019344 ISS cysteine biosynthetic process
GO:0030170 ISS pyridoxal phosphate binding
GO:0043066 IMP negative regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044524 IMP protein sulfhydration
GO:0044540 IMP L-cystine L-cysteine-lyase (deaminating)
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051289 IEA protein homotetramerization
GO:0070062 IEA extracellular vesicular exosome
GO:0070814 ISS hydrogen sulfide biosynthetic process
GO:0080146 IEA L-cysteine desulfhydrase activity
GO:2001234 IMP negative regulation of apoptotic signaling pathway

Homologs

No Homologs available.

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