C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: furin (paired basic amino acid cleaving enzyme)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120753 Furin-002 ENSMUSG00000030530 10090 - 7:80389196-80401707 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AY CIL_0008AY_0002 VISTA 7:80145068-80746500

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0004175 IEA endopeptidase activity
GO:0004252 IBA serine-type endopeptidase activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IBA extracellular space
GO:0005769 TAS early endosome
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IBA Golgi apparatus
GO:0005802 IEA trans-Golgi network
GO:0005886 IEA plasma membrane
GO:0006465 IEA signal peptide processing
GO:0006508 IBA:IEA proteolysis
GO:0008233 ISO peptidase activity
GO:0008283 IEA cell proliferation
GO:0009966 IDA regulation of signal transduction
GO:0009986 IEA cell surface
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0012510 TAS trans-Golgi network transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 TAS integral component of membrane
GO:0016485 ISO protein processing
GO:0016486 IEA peptide hormone processing
GO:0019058 IEA viral life cycle
GO:0030140 ISO trans-Golgi network transport vesicle
GO:0032804 IEA negative regulation of low-density lipoprotein particle receptor catabolic process
GO:0032902 IEA nerve growth factor production
GO:0032911 IEA negative regulation of transforming growth factor beta1 production
GO:0032940 IEA secretion by cell
GO:0042176 IEA regulation of protein catabolic process
GO:0042277 IEA peptide binding
GO:0043043 IEA peptide biosynthetic process
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0048406 IEA nerve growth factor binding
GO:0052548 IEA regulation of endopeptidase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000268171 FURIN-001 protein_coding Homo_sapiens 0 3463
ENST00000558794 FURIN-002 nonsense_mediated_decay Homo_sapiens 0 830
ENST00000559353 FURIN-003 protein_coding Homo_sapiens 0 420
ENST00000560824 FURIN-005 protein_coding Homo_sapiens 0 671
ENST00000610579 FURIN-201 protein_coding Homo_sapiens 0 3463
ENST00000618099 FURIN-202 protein_coding Homo_sapiens 0 3463

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