C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: c-abl oncogene 1, non-receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000124089 Abl1-009 ENSMUSG00000026842 10090 + 2:31760173-31779024 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000936 CIL_000936_0002 VISTA 2:31199311-31800827
CIL_0008XQ CIL_0008XQ_0002 VISTA 2:31340644-31941311
CIL_0007CW CIL_0007CW_0003 CGP 2:31670715-31804227
CIL_0006I2 CIL_0006I2_0002 CGP 2:31688376-31810580

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001922 IMP B-1 B cell homeostasis
GO:0002322 IMP B cell proliferation involved in immune response
GO:0002333 IMP transitional one stage B cell differentiation
GO:0004672 IDA protein kinase activity
GO:0004713 IMP protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 ISA cytosol
GO:0006909 IMP phagocytosis
GO:0006979 IMP response to oxidative stress
GO:0007173 IGI epidermal growth factor receptor signaling pathway
GO:0015629 IDA actin cytoskeleton
GO:0016301 IDA kinase activity
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019904 IPI protein domain specific binding
GO:0021587 IGI cerebellum morphogenesis
GO:0022408 IGI negative regulation of cell-cell adhesion
GO:0030035 IDA microspike assembly
GO:0030514 IMP negative regulation of BMP signaling pathway
GO:0031252 IDA cell leading edge
GO:0032956 IGI regulation of actin cytoskeleton organization
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0042100 IMP B cell proliferation
GO:0043065 IMP positive regulation of apoptotic process
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0045931 IGI positive regulation of mitotic cell cycle
GO:0046632 IGI alpha-beta T cell differentiation
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048536 IMP spleen development
GO:0048538 IMP thymus development
GO:0048668 IMP collateral sprouting
GO:0050798 IMP activated T cell proliferation
GO:0050853 IMP B cell receptor signaling pathway
GO:0050885 IGI neuromuscular process controlling balance
GO:0051015 IDA actin filament binding
GO:0051281 IGI positive regulation of release of sequestered calcium ion into cytosol
GO:0051726 IDA regulation of cell cycle
GO:0060020 IGI Bergmann glial cell differentiation
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0090135 IMP actin filament branching
GO:1900042 IGI positive regulation of interleukin-2 secretion
GO:1901216 IMP positive regulation of neuron death
GO:1902715 IGI positive regulation of interferon-gamma secretion
GO:1903053 IGI regulation of extracellular matrix organization
GO:2000096 IGI positive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000352 IGI negative regulation of endothelial cell apoptotic process
GO:2000772 IGI regulation of cellular senescence
GO:2000773 IGI negative regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000318560 ABL1-001 protein_coding Homo_sapiens 0 399
ENST00000372348 ABL1-002 protein_coding Homo_sapiens 0 399

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