C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: receptor (calcitonin) activity modifying protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000129680 Ramp2-001 ENSMUSG00000001240 10090 + 11:101246028-101248250 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000129680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000129680 48.669±10.25 10.038±1.44 25.173±7.31 12.213±1.10 27.358±2.91 11.524±1.72 14.468±3.75 13.207±1.39 7.470±0.68 139.181±34.78 10.814±1.38 31.666±4.19 15.595±0.97 2.544±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IN CIL_0004IN_0002 CGP 11:101191115-101259546
CIL_0004JZ CIL_0004JZ_0002 CGP 11:101246028-101259549

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0001570 IEA vasculogenesis
GO:0001666 IEA response to hypoxia
GO:0002040 IMP sprouting angiogenesis
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0006171 ISS cAMP biosynthetic process
GO:0006816 ISS calcium ion transport
GO:0006886 IEA intracellular protein transport
GO:0007186 IPI G-protein coupled receptor signaling pathway
GO:0007507 IMP heart development
GO:0007565 IEA female pregnancy
GO:0008217 IMP regulation of blood pressure
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008565 IEA:ISS protein transporter activity
GO:0009986 ISS cell surface
GO:0010628 IMP positive regulation of gene expression
GO:0015026 IDA coreceptor activity
GO:0015031 ISS protein transport
GO:0016021 IEA integral component of membrane
GO:0030819 ISS positive regulation of cAMP biosynthetic process
GO:0031623 ISS receptor internalization
GO:0032355 IEA response to estradiol
GO:0032570 IEA response to progesterone
GO:0032870 IEA cellular response to hormone stimulus
GO:0034333 IMP adherens junction assembly
GO:0035924 IMP cellular response to vascular endothelial growth factor stimulus
GO:0043116 IMP negative regulation of vascular permeability
GO:0043235 ISS receptor complex
GO:0045766 IMP positive regulation of angiogenesis
GO:0070830 IMP tight junction assembly
GO:0070831 IMP basement membrane assembly
GO:0072659 ISS protein localization to plasma membrane
GO:0097084 IMP vascular smooth muscle cell development
GO:2000352 IMP negative regulation of endothelial cell apoptotic process
GO:2001214 IMP positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000253796 RAMP2-001 protein_coding Homo_sapiens 0 318
ENST00000587142 RAMP2-002 protein_coding Homo_sapiens 0 309
ENST00000588576 RAMP2-003 protein_coding Homo_sapiens 0 281
ENST00000589683 RAMP2-004 protein_coding Homo_sapiens 0 327

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