C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: promyelocytic leukemia
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000135310 Pml-004 ENSMUSG00000036986 10090 - 9:58218086-58249733 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaENSMUST00000135310
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENSMUST00000135310 2.231±0.54 5.919±1.58 1.139±0.39 0.363±0.00 5.125±2.29 3.557±1.54 3.156±1.46 2.342±0.92 2.302±0.61 5.355±1.18 0.701±0.25

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IMP response to hypoxia
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007182 IMP common-partner SMAD protein phosphorylation
GO:0007184 IMP SMAD protein import into nucleus
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 IMP response to UV
GO:0010332 IMP response to gamma radiation
GO:0016363 IDA nuclear matrix
GO:0016525 IMP negative regulation of angiogenesis
GO:0016605 IDA PML body
GO:0030099 IMP myeloid cell differentiation
GO:0030578 IDA PML body organization
GO:0045165 IMP cell fate commitment
GO:0045343 IDA regulation of MHC class I biosynthetic process
GO:0046332 IDA SMAD binding
GO:0048384 IMP retinoic acid receptor signaling pathway
GO:0051457 ISO maintenance of protein location in nucleus
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071353 IDA cellular response to interleukin-4
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097191 IMP extrinsic apoptotic signaling pathway
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000268058 PML-001 protein_coding Homo_sapiens 0 1550
ENST00000359928 PML-013 protein_coding Homo_sapiens 1.99993e-41 174
ENST00000395135 PML-006 protein_coding Homo_sapiens 0 1044
ENST00000564428 PML-012 protein_coding Homo_sapiens 0 270
ENST00000565317 PML-021 processed_transcript Homo_sapiens 4e-30 135
ENST00000565898 PML-005 protein_coding Homo_sapiens 0 776
ENST00000569965 PML-008 protein_coding Homo_sapiens 0 1013

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