C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: promyelocytic leukemia
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000569965 PML-008 ENSG00000140464 9606 + 15:73994733-74043338 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0001932 ISS regulation of protein phosphorylation
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0003677 IEA DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006461 IDA protein complex assembly
GO:0006605 IDA protein targeting
GO:0006915 IDA apoptotic process
GO:0006977 ISS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007050 IDA cell cycle arrest
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0008630 IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010522 ISS regulation of calcium ion transport into cytosol
GO:0016032 IEA viral process
GO:0016363 IDA nuclear matrix
GO:0016525 IMP negative regulation of angiogenesis
GO:0016605 IDA PML body
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030308 IDA negative regulation of cell growth
GO:0030578 IDA PML body organization
GO:0031065 IDA positive regulation of histone deacetylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031965 IDA nuclear membrane
GO:0032183 IPI SUMO binding
GO:0032211 IMP negative regulation of telomere maintenance via telomerase
GO:0032469 ISS endoplasmic reticulum calcium ion homeostasis
GO:0032922 ISS circadian regulation of gene expression
GO:0032938 IDA negative regulation of translation in response to oxidative stress
GO:0034097 IDA response to cytokine
GO:0042406 ISS extrinsic component of endoplasmic reticulum membrane
GO:0042752 ISS regulation of circadian rhythm
GO:0042771 ISS intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042803 IPI protein homodimerization activity
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 IDA innate immune response
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0046982 IDA protein heterodimerization activity
GO:0050821 IDA protein stabilization
GO:0050897 IDA cobalt ion binding
GO:0051457 IDA maintenance of protein location in nucleus
GO:0051607 IEA defense response to virus
GO:0051974 IMP negative regulation of telomerase activity
GO:0060058 IDA positive regulation of apoptotic process involved in mammary gland involution
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0090398 IDA cellular senescence
GO:1902187 IDA negative regulation of viral release from host cell
GO:2000059 IMP negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000779 IMP regulation of double-strand break repair
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000153820 Pml-003 protein_coding Mus_musculus 0 1042
ENSMUST00000135310 Pml-004 protein_coding Mus_musculus 0 1013
ENSMUST00000085673 Pml-001 protein_coding Mus_musculus 0 1013
ENSMUST00000126690 Pml-005 protein_coding Mus_musculus 0 239
ENSMUST00000114136 Pml-002 protein_coding Mus_musculus 0 239

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