C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myocyte enhancer factor 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000135493 Mef2a-007 ENSMUSG00000030557 10090 - 7:67232084-67316920 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartTestisENSMUST00000135493
Transcript ID Colon Heart Testis
ENSMUST00000135493 2.101±0.07 8.569±0.00 3.110±0.64

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000002 IMP mitochondrial genome maintenance
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000165 ISS MAPK cascade
GO:0000790 IDA nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:IC RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC:IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007399 IEA nervous system development
GO:0019901 IPI protein kinase binding
GO:0033613 IPI activating transcription factor binding
GO:0035035 ISS histone acetyltransferase binding
GO:0042826 ISS histone deacetylase binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI:IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 ISS SMAD binding
GO:0048311 IMP mitochondrion distribution
GO:0055005 IMP ventricular cardiac myofibril assembly
GO:0061337 IMP cardiac conduction
GO:0070375 ISS ERK5 cascade
GO:0071277 ISS cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000338042 MEF2A-201 protein_coding Homo_sapiens 0 1951
ENST00000354410 MEF2A-001 protein_coding Homo_sapiens 0 1618
ENST00000449277 MEF2A-004 protein_coding Homo_sapiens 0 1541
ENST00000557785 MEF2A-002 protein_coding Homo_sapiens 0 1951
ENST00000557942 MEF2A-005 protein_coding Homo_sapiens 0 2100
ENST00000558812 MEF2A-003 protein_coding Homo_sapiens 0 1690
ENST00000558983 MEF2A-012 retained_intron Homo_sapiens 0 652
ENST00000559036 MEF2A-006 retained_intron Homo_sapiens 0 414
ENST00000559903 MEF2A-009 protein_coding Homo_sapiens 0 385
ENST00000560493 MEF2A-008 protein_coding Homo_sapiens 0 409
ENST00000561125 MEF2A-007 retained_intron Homo_sapiens 0 778

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