C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000145735 Lamtor5-201 ENSMUSG00000087260 10090 + 3:107278858-107284079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000145735
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000145735 51.435±1.32 27.469±3.81 48.250±5.86 20.436±11.53 38.983±8.61 40.701±4.26 33.810±2.93 109.563±8.73 29.384±5.64 49.490±2.08 33.153±1.00 42.170±7.57 33.762±12.93 28.102±11.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00075T CIL_00075T_0002 CGP 3:107235531-107284079
CIL_00075S CIL_00075S_0002 CGP 3:107278858-107312115

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005764 ISS lysosome
GO:0005829 IEA cytosol
GO:0008361 ISS regulation of cell size
GO:0019079 IEA viral genome replication
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 ISS positive regulation of GTPase activity
GO:0061462 ISS protein localization to lysosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000256644 LAMTOR5-001 protein_coding Homo_sapiens 0 435
ENST00000444290 LAMTOR5P1-001 processed_pseudogene Homo_sapiens 0 289
ENST00000464240 LAMTOR5-002 retained_intron Homo_sapiens 0 355
ENST00000474861 LAMTOR5-003 protein_coding Homo_sapiens 0 355
ENST00000483260 LAMTOR5-004 protein_coding Homo_sapiens 0 355
ENST00000531779 LAMTOR5-006 retained_intron Homo_sapiens 0 305
ENST00000602318 LAMTOR5-007 protein_coding Homo_sapiens 0 409
ENST00000602858 LAMTOR5-008 protein_coding Homo_sapiens 0 355
ENST00000614544 LAMTOR5-201 protein_coding Homo_sapiens 0 435

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