C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Transcript Info |
||||||
| Description: | phosphodiesterase 4B, cAMP specific | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENSMUST00000173119  |
Pde4b-010 |
ENSMUSG00000028525 |
10090 | + |
4:102087741-102557597  |
nonsense_mediated_decay |
Expression PatternsNo expression data. |
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_0002NS | CIL_0002NS_0002 | CGP | 4:102087543-102973628 |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0001780 | IMP | neutrophil homeostasis |
| GO:0004115 | ISS | 3',5'-cyclic-AMP phosphodiesterase activity |
| GO:0008152 | ISS | metabolic process |
| GO:0030593 | IMP | neutrophil chemotaxis |
| GO:0035690 | IDA | cellular response to drug |
| GO:0050900 | IMP | leukocyte migration |
| GO:0071222 | IMP | cellular response to lipopolysaccharide |
| GO:0071944 | IDA | cell periphery |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENST00000329654
|
PDE4B-001 | protein_coding | Homo_sapiens | 0 | 599 |
|
ENST00000341517
|
PDE4B-002 | protein_coding | Homo_sapiens | 0 | 599 |
|
ENST00000532040
|
PDE4B-012 | processed_transcript | Homo_sapiens | 7e-27 | 124 |
