C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000177129 Tirap-002 ENSMUSG00000032041 10090 - 9:35186785-35199988 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007W7 CIL_0007W7_0002 VISTA 9:35123876-35727017

Gene Ontology

GO IDEvidence TypeGO Description
GO:0007166 IPI cell surface receptor signaling pathway
GO:0007249 IMP I-kappaB kinase/NF-kappaB signaling
GO:0007257 ISO activation of JUN kinase activity
GO:0009617 ISO response to bacterium
GO:0030099 IMP myeloid cell differentiation
GO:0032760 IMP positive regulation of tumor necrosis factor production
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0071221 IMP cellular response to bacterial lipopeptide
GO:0071223 IMP cellular response to lipoteichoic acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000392678 TIRAP-003 protein_coding Homo_sapiens 0 407
ENST00000392679 TIRAP-001 protein_coding Homo_sapiens 0 431
ENST00000392680 TIRAP-002 protein_coding Homo_sapiens 0 431
ENST00000479770 TIRAP-008 nonsense_mediated_decay Homo_sapiens 0 431

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