C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: c-src tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000220003 CSK-001 ENSG00000103653 9606 + 15:74782057-74803198 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220003
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220003 9.082±0.00 43.741±0.00 2.518±0.00 2.459±1.70 4.781±0.00 2.582±2.48 7.027±0.00 14.198±0.00 9.581±0.00 1.923±0.00 13.184±9.18 11.889±3.47 9.595±3.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0001 VISTA 15:74278506-74880453

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IPI plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006468 TAS:IEA protein phosphorylation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007420 IEA brain development
GO:0007596 TAS blood coagulation
GO:0008022 TAS protein C-terminus binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0010989 IEA negative regulation of low-density lipoprotein particle clearance
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IEA protein phosphatase binding
GO:0030168 TAS platelet activation
GO:0031295 TAS T cell costimulation
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0033673 IEA negative regulation of kinase activity
GO:0034332 IEA adherens junction organization
GO:0042802 IPI identical protein binding
GO:0042997 IDA negative regulation of Golgi to plasma membrane protein transport
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045121 IEA membrane raft
GO:0045779 IEA negative regulation of bone resorption
GO:0046777 IEA protein autophosphorylation
GO:0048709 IEA oligodendrocyte differentiation
GO:0050765 IEA negative regulation of phagocytosis
GO:0050852 TAS T cell receptor signaling pathway
GO:0060368 IEA regulation of Fc receptor mediated stimulatory signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070064 IEA proline-rich region binding
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0071375 IEA cellular response to peptide hormone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034863 Csk-201 protein_coding Mus_musculus 0 2977
ENSDART00000104271 csk-001 protein_coding Danio_rerio 0 863
ENSDART00000098076 CSK (1 of 2)-201 protein_coding Danio_rerio 0 529

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