C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class II, DO alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000229829 HLA-DOA-001 ENSG00000204252 9606 - 6:33004178-33009612 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000229829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000229829 3.406±0.00 24.164±0.00 0.404±0.00 1.406±1.23 2.667±1.04 0.988±0.00 1.293±0.88 3.232±2.39 0.567±0.21 7.579±2.94 0.202±0.08 2.718±1.97 1.386±0.67 0.721±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PI CIL_0001PI_0002 CGP 6:33004178-33080775

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002587 IDA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0032395 TAS MHC class II receptor activity
GO:0042613 IDA:IEA MHC class II protein complex
GO:0045580 IEA regulation of T cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.0000000006 71

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