C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth hormone receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000230882 GHR-001 ENSG00000112964 9606 + 5:42423777-42721877 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartKidneyLiverMuscleOvaryTestisENST00000230882
Transcript ID Adipose Brain Breast Heart Kidney Liver Muscle Ovary Testis
ENST00000230882 27.675±0.00 0.145±0.00 9.390±8.58 0.999±0.66 1.127±0.00 4.481±0.00 5.020±2.95 1.237±0.00 1.513±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0000255 ISS allantoin metabolic process
GO:0004896 IEA cytokine receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IMP extracellular space
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006101 ISS citrate metabolic process
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006105 ISS succinate metabolic process
GO:0006107 ISS oxaloacetate metabolic process
GO:0006549 ISS isoleucine metabolic process
GO:0006573 ISS valine metabolic process
GO:0006600 ISS creatine metabolic process
GO:0006631 ISS fatty acid metabolic process
GO:0006897 IEA endocytosis
GO:0007259 ISS JAK-STAT cascade
GO:0009986 IDA cell surface
GO:0016021 IDA integral component of membrane
GO:0017046 IPI peptide hormone binding
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019530 ISS taurine metabolic process
GO:0019838 IPI growth factor binding
GO:0019901 ISS protein kinase binding
GO:0031623 IDA receptor internalization
GO:0032355 IDA response to estradiol
GO:0032870 IMP cellular response to hormone stimulus
GO:0040014 ISS regulation of multicellular organism growth
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0042517 ISS positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 ISS positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042803 IDA protein homodimerization activity
GO:0042977 ISS activation of JAK2 kinase activity
GO:0043235 IDA receptor complex
GO:0044236 IMP multicellular organismal metabolic process
GO:0046449 ISS creatinine metabolic process
GO:0046898 IDA response to cycloheximide
GO:0048009 IMP insulin-like growth factor receptor signaling pathway
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0060396 IMP growth hormone receptor signaling pathway
GO:0060397 TAS JAK-STAT cascade involved in growth hormone signaling pathway
GO:0070064 ISS proline-rich region binding
GO:0070195 IDA growth hormone receptor complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069451 Ghr-005 protein_coding Mus_musculus 0 1687
ENSMUST00000161561 Ghr-001 protein_coding Mus_musculus 0 1559

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