C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth hormone receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000069451 Ghr-005 ENSMUSG00000055737 10090 - 15:3317760-3583230 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069451 58.627±42.14 9.995±5.53 12.725±0.19 1.315±0.01 34.739±6.86 4.376±0.91 13.124±0.90 39.957±5.50 21.331±15.77 10.951±1.50 23.158±0.70 9.806±3.52 12.447±11.39 0.150±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003B8 CIL_0003B8_0002 CGP 15:3317760-3979573

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0004903 IDA growth hormone receptor activity
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007259 IEA JAK-STAT cascade
GO:0009725 IEA response to hormone
GO:0009755 IEA hormone-mediated signaling pathway
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0017046 IPI peptide hormone binding
GO:0019221 IEA:IDA cytokine-mediated signaling pathway
GO:0019838 IEA growth factor binding
GO:0019898 IDA extrinsic component of membrane
GO:0019901 IEA protein kinase binding
GO:0019903 IEA protein phosphatase binding
GO:0031623 IEA receptor internalization
GO:0032094 IEA response to food
GO:0032355 IEA response to estradiol
GO:0032869 IEA cellular response to insulin stimulus
GO:0032870 IEA cellular response to hormone stimulus
GO:0034097 IEA response to cytokine
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0042169 IEA SH2 domain binding
GO:0042803 IEA protein homodimerization activity
GO:0042976 IEA activation of Janus kinase activity
GO:0042977 IEA activation of JAK2 kinase activity
GO:0043025 IEA neuronal cell body
GO:0043235 IEA receptor complex
GO:0043278 IEA response to morphine
GO:0043434 IEA response to peptide hormone
GO:0044236 IEA multicellular organismal metabolic process
GO:0045597 IEA positive regulation of cell differentiation
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0046898 IEA response to cycloheximide
GO:0048009 IEA insulin-like growth factor receptor signaling pathway
GO:0051384 IEA response to glucocorticoid
GO:0060351 IEA cartilage development involved in endochondral bone morphogenesis
GO:0060396 IEA growth hormone receptor signaling pathway
GO:0070195 IEA growth hormone receptor complex
GO:0070555 IEA response to interleukin-1
GO:1901215 IEA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000230882 GHR-001 protein_coding Homo_sapiens 0 1687
ENST00000357703 GHR-201 protein_coding Homo_sapiens 0 1524
ENST00000511135 GHR-002 nonsense_mediated_decay Homo_sapiens 0 1467
ENST00000537449 GHR-202 protein_coding Homo_sapiens 0 1557
ENST00000612382 GHR-203 protein_coding Homo_sapiens 0 1557
ENST00000612626 GHR-204 protein_coding Homo_sapiens 0 1559
ENST00000615111 GHR-205 protein_coding Homo_sapiens 0 1559
ENST00000618088 GHR-206 protein_coding Homo_sapiens 0 1559
ENST00000620156 GHR-207 protein_coding Homo_sapiens 0 1557
ENST00000622294 GHR-208 protein_coding Homo_sapiens 0 857

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