C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000234454 SPR-001 ENSG00000116096 9606 + 2:72887360-72892158 protein_coding

Homo sapiens EnsemblGRCh38

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Transcripts
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000234454
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000234454 15.698±0.00 8.475±0.00 1.455±0.00 3.138±2.15 13.711±12.32 13.363±8.73 9.353±8.62 19.886±11.90 23.377±20.08 6.621±5.62 23.646±20.95 23.986±18.56 12.330±4.16 11.930±9.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087O CIL_00087O_0001 VISTA 2:72597601-73198962
CIL_0008RW CIL_0008RW_0001 VISTA 2:72647671-73248640
CIL_0003EH CIL_0003EH_0001 CGP 2:72887360-72936071

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0004757 ISS:IEA sepiapterin reductase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006558 IEA L-phenylalanine metabolic process
GO:0006729 TAS:IEA tetrahydrobiopterin biosynthetic process
GO:0006809 IDA nitric oxide biosynthetic process
GO:0008152 IEA metabolic process
GO:0016265 IEA death
GO:0016491 IEA oxidoreductase activity
GO:0019889 IEA pteridine metabolic process
GO:0040014 IEA regulation of multicellular organism growth
GO:0042415 IEA norepinephrine metabolic process
GO:0042417 IEA dopamine metabolic process
GO:0042428 IEA serotonin metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046146 IEA tetrahydrobiopterin metabolic process
GO:0046209 TAS nitric oxide metabolic process
GO:0048667 IEA cell morphogenesis involved in neuron differentiation
GO:0050661 TAS NADP binding
GO:0050882 IEA voluntary musculoskeletal movement
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0055114 TAS:IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

No Homologs available.

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