C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: regulator of G-protein signaling 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000235382 RGS2-001 ENSG00000116741 9606 + 1:192809041-192812283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000235382
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000235382 6.949±0.00 7.772±0.00 3.391±0.00 7.375±1.85 15.827±2.48 43.148±36.05 4.441±4.02 9.924±8.47 13.650±11.42 32.257±23.57 0.616±0.11 33.594±24.81 28.404±5.88 21.635±9.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001BS CIL_0001BS_0002 CGP 1:192636138-192812283
CIL_0001BR CIL_0001BR_0002 CGP 1:192809039-193060080

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005516 TAS calmodulin binding
GO:0005634 IEA nucleus
GO:0005737 IBA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 ISS cytosol
GO:0005886 IBA plasma membrane
GO:0006417 IEA regulation of translation
GO:0007049 IEA cell cycle
GO:0007283 IEA spermatogenesis
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0009898 ISS cytoplasmic side of plasma membrane
GO:0010519 ISS negative regulation of phospholipase activity
GO:0010614 ISS negative regulation of cardiac muscle hypertrophy
GO:0031116 IEA positive regulation of microtubule polymerization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0043951 IEA negative regulation of cAMP-mediated signaling
GO:0045744 ISS negative regulation of G-protein coupled receptor protein signaling pathway
GO:0048487 IEA beta-tubulin binding
GO:0050873 IEA brown fat cell differentiation
GO:0055119 ISS relaxation of cardiac muscle
GO:0060087 IEA relaxation of vascular smooth muscle
GO:0060452 ISS positive regulation of cardiac muscle contraction
GO:0071877 ISS regulation of adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000127206 Rgs2-001 protein_coding Mus_musculus 0 1122
ENSMUST00000153527 Rgs2-003 protein_coding Mus_musculus 0 470
ENSMUST00000027606 Rgs2-004 nonsense_mediated_decay Mus_musculus 0 254
ENSMUST00000134817 Rgs2-002 retained_intron Mus_musculus 0 252

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