C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: matrix metallopeptidase 24 (membrane-inserted)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000246186 MMP24-001 ENSG00000125966 9606 + 20:35226654-35277000 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartKidneyLiverLungTestisENST00000246186
Transcript ID Bladder Brain Colon Heart Kidney Liver Lung Testis
ENST00000246186 2.193±0.00 5.922±2.61 3.276±0.00 1.829±0.00 6.581±5.35 0.788±0.00 3.496±2.42 4.712±1.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EI CIL_0008EI_0001 VISTA 20:35018152-35620688
CIL_00030R CIL_00030R_0001 CGP 20:35172073-35277000
CIL_0002HV CIL_0002HV_0001 CGP 20:35226654-35284985

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004222 ISS:IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005887 ISS integral component of plasma membrane
GO:0006508 ISS:IEA proteolysis
GO:0008047 TAS enzyme activator activity
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0010001 ISS glial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0032588 ISS trans-Golgi network membrane
GO:0043085 TAS positive regulation of catalytic activity
GO:0044331 ISS cell-cell adhesion mediated by cadherin
GO:0045296 IEA cadherin binding
GO:0050965 ISS detection of temperature stimulus involved in sensory perception of pain
GO:0070062 IDA extracellular vesicular exosome
GO:0097150 ISS neuronal stem cell maintenance
GO:0098609 ISS cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029141 Mmp24-001 protein_coding Mus_musculus 0 3171
ENSMUST00000135945 Mmp24-002 retained_intron Mus_musculus 0 337

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