C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: multiple EGF-like-domains 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000251268 MEGF8-002 ENSG00000105429 9606 + 19:42326244-42377786 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyMuscleENST00000251268
Transcript ID Colon Kidney Muscle
ENST00000251268 0.223±0.00 0.692±0.00 0.495±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005V6 CIL_0005V6_0001 CGP 19:42313325-42378769
CIL_00053T CIL_00053T_0001 CGP 19:42325609-42390287

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003143 ISS embryonic heart tube morphogenesis
GO:0004872 IEA receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0007275 IEA multicellular organismal development
GO:0010468 ISS regulation of gene expression
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030326 ISS embryonic limb morphogenesis
GO:0030509 ISS BMP signaling pathway
GO:0035108 IMP limb morphogenesis
GO:0042074 IMP cell migration involved in gastrulation
GO:0048704 ISS embryonic skeletal system morphogenesis
GO:0048842 ISS positive regulation of axon extension involved in axon guidance
GO:0055113 IMP epiboly involved in gastrulation with mouth forming second
GO:0060971 ISS embryonic heart tube left/right pattern formation
GO:0060972 IMP left/right pattern formation
GO:0061371 IMP determination of heart left/right asymmetry
GO:0070062 IDA extracellular vesicular exosome
GO:0071907 ISS determination of digestive tract left/right asymmetry
GO:0097094 IMP craniofacial suture morphogenesis
GO:0097155 ISS fasciculation of sensory neuron axon

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000128119 Megf8-001 protein_coding Mus_musculus 0 6231
ENSMUST00000153077 Megf8-002 retained_intron Mus_musculus 0 3766
ENSDART00000110951 megf8-203 protein_coding Danio_rerio 8e-33 148
ENSDART00000142056 megf8-001 protein_coding Danio_rerio 8e-33 148

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