C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 6B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000254846 KDM6B-001 ENSG00000132510 9606 + 17:7839904-7854796 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastKidneyLiverLungOvaryPlacentaTestisENST00000254846
Transcript ID Adipose Breast Kidney Liver Lung Ovary Placenta Testis
ENST00000254846 3.201±0.00 0.996±0.00 1.594±0.00 0.217±0.00 10.662±0.00 7.432±3.54 2.495±0.71 5.950±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00037F CIL_00037F_0002 CGP 17:7717354-7854796
CIL_000322 CIL_000322_0002 CGP 17:7839904-7856099

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0006954 IEA inflammatory response
GO:0008013 IEA beta-catenin binding
GO:0016577 IEA histone demethylation
GO:0043565 IEA sequence-specific DNA binding
GO:0045446 ISS endothelial cell differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048333 ISS mesodermal cell differentiation
GO:0051213 IEA dioxygenase activity
GO:0055007 ISS cardiac muscle cell differentiation
GO:0055114 IEA oxidation-reduction process
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071557 IEA histone H3-K27 demethylation
GO:0071558 EXP histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000094077 Kdm6b-001 protein_coding Mus_musculus 0 6174
ENSMUST00000156562 Kdm6b-002 processed_transcript Mus_musculus 0 595
ENSDART00000088469 kdm6a-201 protein_coding Danio_rerio 0 261
ENSDART00000144623 kdm6a-001 protein_coding Danio_rerio 0 261

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