C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000256383 EIF2S1-003 ENSG00000134001 9606 + 14:67359997-67386516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256383
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256383 11.985±0.00 11.441±0.00 1.990±0.00 9.428±1.24 7.873±2.21 6.492±2.37 6.039±2.54 6.120±2.31 7.191±2.71 7.206±1.81 7.027±5.18 6.297±1.66 5.838±0.60 14.401±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010H CIL_00010H_0001 CGP 14:67241109-67360265
CIL_0001KG CIL_0001KG_0002 CGP 14:67294371-67386516
CIL_00010S CIL_00010S_0001 CGP 14:67359997-67412200

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0003743 IEA:IDA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005844 TAS polysome
GO:0005850 IEA eukaryotic translation initiation factor 2 complex
GO:0005851 IDA eukaryotic translation initiation factor 2B complex
GO:0006412 TAS translation
GO:0006413 IEA:TAS translational initiation
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0010467 TAS gene expression
GO:0010494 ISS cytoplasmic stress granule
GO:0016020 IDA membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0043022 IDA ribosome binding
GO:0043558 IEA regulation of translational initiation in response to stress
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0046777 IEA protein autophosphorylation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071230 Eif2s1-001 protein_coding Mus_musculus 0 1877
ENSMUST00000120228 Gm12734-001 processed_pseudogene Mus_musculus 0 1330
ENSMUST00000119314 Gm13915-001 processed_pseudogene Mus_musculus 0 1136
ENSMUST00000122405 Gm13602-001 processed_pseudogene Mus_musculus 0 599
ENSMUST00000186994 RP23-275F9.1-001 processed_pseudogene Mus_musculus 0 416

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