C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ADAM metallopeptidase with thrombospondin type 1 motif, 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000257359 ADAMTS8-001 ENSG00000134917 9606 - 11:130404925-130428993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000257359
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000257359 0.339±0.00 0.854±0.00 1.890±0.69 0.186±0.02 2.441±2.06 0.236±0.00 2.622±0.00 0.134±0.11 31.699±29.88 1.716±0.94 4.541±0.40 0.969±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000517 CIL_000517_0002 CGP 11:130226677-130428993
CIL_000516 CIL_000516_0002 CGP 11:130404925-130476641

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 TAS integrin binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008201 IEA heparin binding
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0009673 TAS low-affinity phosphate transmembrane transporter activity
GO:0031012 ISS:IEA extracellular matrix
GO:0035435 TAS phosphate ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000068135 Adamts8-001 protein_coding Mus_musculus 0 2194
ENSMUST00000163037 Adamts8-002 nonsense_mediated_decay Mus_musculus 0 1674

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