C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Cbl proto-oncogene, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264033 CBL-001 ENSG00000110395 9606 + 11:119206042-119308149 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264033
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264033 5.652±0.00 3.095±0.00 1.300±0.00 2.354±0.46 2.180±0.82 2.763±0.10 1.051±0.37 1.677±0.43 0.902±0.09 3.038±0.59 0.750±0.33 2.092±1.11 2.098±0.34 11.358±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021V CIL_00021V_0002 CGP 11:119189638-119308149
CIL_000220 CIL_000220_0002 CGP 11:119206042-119321521

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 IEA phosphotyrosine binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007166 TAS:IEA cell surface receptor signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008270 IEA zinc ion binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016567 IEA protein ubiquitination
GO:0016600 ISS flotillin complex
GO:0016874 IEA ligase activity
GO:0017124 IPI SH3 domain binding
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0043066 IMP negative regulation of apoptotic process
GO:0046872 IEA metal ion binding
GO:0046875 IPI ephrin receptor binding
GO:0048260 TAS positive regulation of receptor-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037644 Cbl-201 protein_coding Mus_musculus 0 3640
ENSMUST00000177264 Gm6695-001 processed_pseudogene Mus_musculus 0 1550
ENSMUST00000120865 Gm15272-001 processed_pseudogene Mus_musculus 0 230

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