C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Cbl proto-oncogene B, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264122 CBLB-001 ENSG00000114423 9606 - 3:105655461-105869043 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264122
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264122 4.148±0.00 2.128±0.00 0.689±0.00 0.469±0.05 1.673±0.45 3.669±0.00 2.762±1.76 1.237±0.56 1.411±0.81 2.066±0.25 0.638±0.50 1.445±0.45 1.646±0.42 2.639±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 IEA phosphotyrosine binding
GO:0002669 IEA positive regulation of T cell anergy
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006607 TAS NLS-bearing protein import into nucleus
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0035556 IEA intracellular signal transduction
GO:0042110 IEA T cell activation
GO:0045732 IEA positive regulation of protein catabolic process
GO:0046642 IEA negative regulation of alpha-beta T cell proliferation
GO:0046872 IEA metal ion binding
GO:0050860 IEA negative regulation of T cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114471 Cblb-201 protein_coding Mus_musculus 0 2765
ENSMUST00000177264 Gm6695-001 processed_pseudogene Mus_musculus 0 394

Loading