C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucokinase (hexokinase 4) regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264717 GCKR-001 ENSG00000084734 9606 + 2:27496842-27523684 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyLiverOvaryPlacentaTestisENST00000264717
Transcript ID Brain Kidney Liver Ovary Placenta Testis
ENST00000264717 0.092±0.00 9.149±0.00 28.704±0.00 0.710±0.59 0.017±0.00 0.494±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DA CIL_0001DA_0001 CGP 2:27491883-27523684

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 ISS protein import into nucleus, translocation
GO:0001678 IEA cellular glucose homeostasis
GO:0004857 IEA enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 ISS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0008645 TAS hexose transport
GO:0009750 IDA response to fructose
GO:0010827 TAS regulation of glucose transport
GO:0015758 TAS glucose transport
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0030246 IEA carbohydrate binding
GO:0033132 IDA negative regulation of glucokinase activity
GO:0033133 IEA positive regulation of glucokinase activity
GO:0034504 IEA protein localization to nucleus
GO:0043086 IEA negative regulation of catalytic activity
GO:0044281 TAS small molecule metabolic process
GO:0046415 IMP urate metabolic process
GO:0055085 TAS transmembrane transport
GO:0070095 IDA fructose-6-phosphate binding
GO:0070328 IMP triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072228 Gckr-201 protein_coding Mus_musculus 0 1657

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