C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polo-like kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000274289 PLK2-001 ENSG00000145632 9606 - 5:58453982-58460260 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000274289
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000274289 1.387±0.00 2.948±0.00 12.203±2.46 6.160±0.22 1.771±0.11 3.300±0.08 2.281±1.12 8.670±2.45 5.711±3.20 13.585±1.57 14.794±5.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000278 IEA mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004871 IMP signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005622 ISS intracellular
GO:0005813 IDA centrosome
GO:0005814 IDA centriole
GO:0006468 IDA:IEA protein phosphorylation
GO:0007052 IDA mitotic spindle organization
GO:0007093 ISS mitotic cell cycle checkpoint
GO:0007265 ISS Ras protein signal transduction
GO:0007613 ISS memory
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030425 ISS dendrite
GO:0032092 IEA positive regulation of protein binding
GO:0032403 IEA protein complex binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032486 ISS Rap protein signal transduction
GO:0043066 ISS negative regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046599 IMP regulation of centriole replication
GO:0048167 ISS regulation of synaptic plasticity
GO:0060291 ISS long-term synaptic potentiation
GO:0060292 ISS long term synaptic depression
GO:0061000 IEA negative regulation of dendritic spine development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022212 Plk2-201 protein_coding Mus_musculus 0 3166

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