Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	sodium channel, voltage-gated, type II, beta subunit
ENST00000278947	SCN2B-001	ENSG00000149575	9606	-	11:118161951-118176673	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000278947	0.053±0.00	0.301±0.00	0.037±0.00	13.785±6.98	0.292±0.08	1.078±1.05	1.156±0.45	0.340±0.00	0.066±0.05	0.248±0.16	0.534±0.12	0.287±0.25	0.046±0.03	0.333±0.22

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_00081E	CIL_00081E_0001	VISTA	11:118137591-118740525

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001518	IDA	voltage-gated sodium channel complex
GO:0005248	IEA	voltage-gated sodium channel activity
GO:0005515	IEA	protein binding
GO:0007268	TAS	synaptic transmission
GO:0007399	IEA	nervous system development
GO:0017080	IDA	sodium channel regulator activity
GO:0035725	IDA	sodium ion transmembrane transport
GO:0046684	IEA	response to pyrethroid
GO:0060048	IMP	cardiac muscle contraction
GO:0060371	IMP	regulation of atrial cardiac muscle cell membrane depolarization
GO:0086002	IMP	cardiac muscle cell action potential involved in contraction
GO:0086006	IMP	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012	IMP	membrane depolarization during cardiac muscle cell action potential
GO:0086091	IMP	regulation of heart rate by cardiac conduction
GO:2000649	IDA	regulation of sodium ion transmembrane transporter activity

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000170998	Scn2b-202	protein_coding	Mus_musculus	0	1009
ENSMUST00000093855	Scn2b-201	protein_coding	Mus_musculus	0	1000

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