C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: apoptosis-inducing factor, mitochondrion-associated, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000287295 AIFM1-001 ENSG00000156709 9606 - X:130129370-130165887 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000287295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000287295 8.341±0.00 9.088±0.00 4.397±0.00 3.006±0.00 7.196±6.39 4.630±0.52 13.069±10.68 16.478±11.43 8.065±7.10 2.059±1.58 8.059±5.37 9.207±6.04 10.594±2.98 11.789±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SZ CIL_0000SZ_0001 CGP X:130064874-130165887
CIL_0000SY CIL_0000SY_0001 CGP X:130129362-130184870

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005758 IDA mitochondrial intermembrane space
GO:0005829 ISS cytosol
GO:0006308 TAS DNA catabolic process
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006915 IMP apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0009055 TAS electron carrier activity
GO:0010942 IEA positive regulation of cell death
GO:0016174 TAS NAD(P)H oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0016651 IDA oxidoreductase activity, acting on NAD(P)H
GO:0030182 IDA neuron differentiation
GO:0030261 TAS chromosome condensation
GO:0032981 IMP mitochondrial respiratory chain complex I assembly
GO:0043065 TAS positive regulation of apoptotic process
GO:0045454 IEA cell redox homeostasis
GO:0046983 IEA protein dimerization activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051402 IEA neuron apoptotic process
GO:0055114 IEA oxidation-reduction process
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071949 IEA FAD binding
GO:1902510 IEA regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037349 Aifm1-001 protein_coding Mus_musculus 0 2582
ENSMUST00000114945 Aifm1-002 protein_coding Mus_musculus 0 2121
ENSMUST00000143466 Aifm1-003 retained_intron Mus_musculus 0 1279
ENSMUST00000156795 Aifm1-004 processed_transcript Mus_musculus 0 1086
ENSDART00000080886 aifm1-202 protein_coding Danio_rerio 0 553
ENSDART00000080882 aifm1-201 protein_coding Danio_rerio 0 553
ENSDART00000131889 aifm1-001 protein_coding Danio_rerio 0 553
ENSMUST00000124623 Aifm1-005 processed_transcript Mus_musculus 0 243

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