C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: frizzled class receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000287934 FZD1-001 ENSG00000157240 9606 + 7:91264364-91271326 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000287934
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000287934 2.306±0.00 2.583±0.00 2.445±0.00 0.688±0.03 2.767±0.87 2.730±1.41 2.412±1.30 3.409±2.92 1.142±0.69 3.127±0.63 0.545±0.24 3.975±2.39 5.587±0.67 4.793±3.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097Q CIL_00097Q_0001 VISTA 7:90686636-91289190
CIL_000866 CIL_000866_0001 VISTA 7:90824580-91428765
CIL_0008EJ CIL_0008EJ_0001 VISTA 7:90847899-91451521
CIL_0008EH CIL_0008EH_0001 VISTA 7:90868556-91471397

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001944 IBA vasculature development
GO:0003149 IEA membranous septum morphogenesis
GO:0003150 IEA muscular septum morphogenesis
GO:0003151 IEA outflow tract morphogenesis
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005102 IPI receptor binding
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IBA Wnt signaling pathway, calcium modulating pathway
GO:0007267 IDA cell-cell signaling
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016055 IEA Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030514 IBA negative regulation of BMP signaling pathway
GO:0030855 IBA epithelial cell differentiation
GO:0032589 IBA neuron projection membrane
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0035425 IDA autocrine signaling
GO:0042493 IMP response to drug
GO:0042813 IDA Wnt-activated receptor activity
GO:0044338 IMP canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339 IMP canonical Wnt signaling pathway involved in osteoblast differentiation
GO:0045177 IBA apical part of cell
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048286 IBA lung alveolus development
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060022 IEA hard palate development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060412 IEA ventricular septum morphogenesis
GO:0090090 IBA negative regulation of canonical Wnt signaling pathway
GO:0090179 IEA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000054294 Fzd1-001 protein_coding Mus_musculus 0 2857
ENSMUST00000057893 Fzd2-001 protein_coding Mus_musculus 0 1199
ENSMUST00000114246 Fzd7-001 protein_coding Mus_musculus 0 808
ENSDART00000060789 fzd1-201 protein_coding Danio_rerio 0 414
ENSDART00000084055 fzd7a-001 protein_coding Danio_rerio 0 351
ENSDART00000156230 fzd9a-201 protein_coding Danio_rerio 3e-31 143
ENSDART00000050970 fzd9a-001 protein_coding Danio_rerio 3e-31 143
ENSDART00000112320 fzd4-201 protein_coding Danio_rerio 7e-22 111

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