C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: angiotensin I converting enzyme
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290863 ACE-007 ENSG00000159640 9606 + 17:63484840-63497618 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastColonOvaryTestisENST00000290863
Transcript ID Adipose Breast Colon Ovary Testis
ENST00000290863 1.054±0.00 5.775±0.00 0.878±0.00 2.392±0.59 50.201±12.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0001 VISTA 17:63374232-63977730
CIL_0006ZU CIL_0006ZU_0001 CGP 17:63432304-63498380

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0001974 IC blood vessel remodeling
GO:0002003 TAS angiotensin maturation
GO:0002005 IC angiotensin catabolic process in blood
GO:0002019 IC regulation of renal output by angiotensin
GO:0003081 IC regulation of systemic arterial blood pressure by renin-angiotensin
GO:0003779 IDA actin binding
GO:0004175 IDA endopeptidase activity
GO:0004180 IEA carboxypeptidase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005768 IDA endosome
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0008144 IDA drug binding
GO:0008217 ISS regulation of blood pressure
GO:0008237 ISS:IEA metallopeptidase activity
GO:0008241 ISS:IEA peptidyl-dipeptidase activity
GO:0008270 IDA zinc ion binding
GO:0009897 IDA external side of plasma membrane
GO:0014910 ISS regulation of smooth muscle cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019229 IC regulation of vasoconstriction
GO:0031404 IDA chloride ion binding
GO:0031711 IPI bradykinin receptor binding
GO:0032943 IC mononuclear cell proliferation
GO:0042312 IC regulation of vasodilation
GO:0042447 ISS hormone catabolic process
GO:0043171 IDA peptide catabolic process
GO:0044267 TAS cellular protein metabolic process
GO:0050482 IDA arachidonic acid secretion
GO:0060218 IC hematopoietic stem cell differentiation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001964 Ace-003 protein_coding Mus_musculus 0 2004
ENSMUST00000001963 Ace-001 protein_coding Mus_musculus 0 1855
ENSMUST00000132280 Ace-002 protein_coding Mus_musculus 0 1640
ENSMUST00000151657 Ace-004 processed_transcript Mus_musculus 0 542

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