C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296280 MASP1-003 ENSG00000127241 9606 - 3:187234082-187291858 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000296280
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000296280 0.403±0.00 0.130±0.00 2.682±2.27 1.569±0.68 4.799±3.60 4.293±3.80 4.507±3.74 2.489±1.46 1.321±0.59 6.243±1.67 0.502±0.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LA CIL_0008LA_0001 VISTA 3:186647123-187250687
CIL_000047 CIL_000047_0001 CGP 3:187217285-187372076

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001867 IMP complement activation, lectin pathway
GO:0003824 IEA catalytic activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0006508 IEA proteolysis
GO:0006956 TAS complement activation
GO:0008233 IDA peptidase activity
GO:0042803 IPI protein homodimerization activity
GO:0045087 TAS innate immune response
GO:0045916 IDA negative regulation of complement activation
GO:0048306 IPI calcium-dependent protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000089883 Masp1-201 protein_coding Mus_musculus 0 1489

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