C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296585 ITGA2-001 ENSG00000164171 9606 + 5:52989326-53094779 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000296585
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000296585 0.102±0.00 1.531±0.00 0.775±0.47 0.642±0.00 0.143±0.12 3.899±0.00 0.646±0.00 1.158±0.62 0.024±0.00 0.804±0.43 0.489±0.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G1 CIL_0007G1_0002 CGP 5:52989326-53110063

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001618 IEA virus receptor activity
GO:0001666 IEA response to hypoxia
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005518 IMP collagen binding
GO:0005634 IEA nucleus
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006928 IEA cellular component movement
GO:0006929 IMP substrate-dependent cell migration
GO:0006971 IEA hypotonic response
GO:0007155 IEA:TAS cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IEA:IMP integrin-mediated signaling pathway
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008283 IEA cell proliferation
GO:0008305 IEA:TAS integrin complex
GO:0009279 IEA cell outer membrane
GO:0009612 IEA response to mechanical stimulus
GO:0009615 IEA response to virus
GO:0009887 TAS organ morphogenesis
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0010694 IEA positive regulation of alkaline phosphatase activity
GO:0014070 IEA response to organic cyclic compound
GO:0014075 IEA response to amine
GO:0014850 IEA response to muscle activity
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0016032 IEA viral process
GO:0030198 TAS extracellular matrix organization
GO:0030424 IEA axon
GO:0030879 IEA mammary gland development
GO:0031346 IEA positive regulation of cell projection organization
GO:0031589 IMP cell-substrate adhesion
GO:0032403 IEA protein complex binding
GO:0032870 IEA cellular response to hormone stimulus
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0033343 IEA positive regulation of collagen binding
GO:0033591 IEA response to L-ascorbic acid
GO:0033627 IMP cell adhesion mediated by integrin
GO:0034666 IDA integrin alpha2-beta1 complex
GO:0038064 IMP collagen receptor activity
GO:0038065 IMP collagen-activated signaling pathway
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043236 IEA laminin binding
GO:0043388 IEA positive regulation of DNA binding
GO:0043589 IEA skin morphogenesis
GO:0043679 IEA axon terminus
GO:0045178 IEA basal part of cell
GO:0045184 IEA establishment of protein localization
GO:0045727 IEA positive regulation of translation
GO:0045785 IEA positive regulation of cell adhesion
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048333 IEP mesodermal cell differentiation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050729 IEA positive regulation of inflammatory response
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0050966 IEA detection of mechanical stimulus involved in sensory perception of pain
GO:0051971 IEA positive regulation of transmission of nerve impulse
GO:0060100 IEA positive regulation of phagocytosis, engulfment
GO:0070365 IEA hepatocyte differentiation
GO:0098639 IMP collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000056117 Itga2-201 protein_coding Mus_musculus 0 3251

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