C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sprouty-related, EVH1 domain containing 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299084 SPRED1-001 ENSG00000166068 9606 + 15:38252326-38357249 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299084
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299084 6.560±0.00 4.776±0.00 1.192±0.00 6.966±0.01 4.709±0.86 3.233±0.68 1.658±0.89 1.845±1.62 2.491±1.77 5.207±2.85 0.285±0.00 3.428±0.49 2.888±0.50 2.796±1.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006QQ CIL_0006QQ_0001 CGP 15:37921939-38357249
CIL_0006QP CIL_0006QP_0001 CGP 15:38252326-38487710

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0005173 ISS stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0009966 IEA regulation of signal transduction
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0010923 IDA negative regulation of phosphatase activity
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0019902 IDA phosphatase binding
GO:0030291 ISS protein serine/threonine kinase inhibitor activity
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 ISS regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028829 Spred1-001 protein_coding Mus_musculus 0 3978
ENSMUST00000110901 Spred1-002 protein_coding Mus_musculus 0 867

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