C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tripeptidyl peptidase I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299427 TPP1-001 ENSG00000166340 9606 - 11:6612763-6619461 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299427
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299427 35.863±0.00 34.671±0.00 6.998±0.00 24.040±20.43 15.320±12.07 15.398±12.73 15.115±14.35 22.231±14.86 16.229±14.88 61.865±0.00 13.077±0.00 18.069±12.41 53.723±17.00 25.088±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003WX CIL_0003WX_0001 CGP 11:6606296-6619461
CIL_0003WC CIL_0003WC_0001 CGP 11:6612763-6655854

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IMP endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005764 IDA lysosome
GO:0006508 IMP:IEA proteolysis
GO:0006629 TAS lipid metabolic process
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007040 ISS lysosome organization
GO:0007399 IMP nervous system development
GO:0008219 IEA cell death
GO:0008233 IMP peptidase activity
GO:0008236 IMP:IEA serine-type peptidase activity
GO:0008240 IMP tripeptidyl-peptidase activity
GO:0030163 NAS protein catabolic process
GO:0030855 IEP epithelial cell differentiation
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0042277 ISS peptide binding
GO:0043171 IMP peptide catabolic process
GO:0043202 TAS lysosomal lumen
GO:0044267 TAS cellular protein metabolic process
GO:0045453 IMP bone resorption
GO:0046872 IEA metal ion binding
GO:0050885 ISS neuromuscular process controlling balance
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033184 Tpp1-201 protein_coding Mus_musculus 0 1927

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