C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CASP8 and FADD-like apoptosis regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000309955 CFLAR-001 ENSG00000003402 9606 + 2:201116104-201176687 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309955
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309955 11.498±0.00 9.774±0.00 1.183±0.34 7.792±4.21 4.284±0.29 3.766±0.00 6.267±3.08 4.095±0.75 9.404±0.00 6.066±2.76 3.647±1.55 3.937±0.62 1.378±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0005123 IEA death receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006508 IEA proteolysis
GO:0006915 IMP:IEA apoptotic process
GO:0007519 ISS skeletal muscle tissue development
GO:0008047 IDA enzyme activator activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0014732 ISS skeletal muscle atrophy
GO:0014842 ISS regulation of satellite cell proliferation
GO:0014866 ISS skeletal myofibril assembly
GO:0016032 IEA viral process
GO:0031264 IDA death-inducing signaling complex
GO:0031265 IEA CD95 death-inducing signaling complex
GO:0032403 IEA protein complex binding
GO:0035877 IBA death effector domain binding
GO:0042981 IEA regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043085 IDA positive regulation of catalytic activity
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043403 ISS skeletal muscle tissue regeneration
GO:0045121 IEA membrane raft
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060544 IDA regulation of necroptotic process
GO:0097190 TAS apoptotic signaling pathway
GO:0097342 IDA ripoptosome
GO:1901740 ISS negative regulation of myoblast fusion
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway
GO:2001239 TAS regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

No Homologs available.

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