C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: endothelin receptor type A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000324300 EDNRA-001 ENSG00000151617 9606 + 4:147480932-147544954 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324300
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324300 3.258±0.00 5.210±0.00 0.165±0.00 0.213±0.00 2.678±2.06 2.448±0.00 2.463±0.00 1.222±0.00 1.500±1.41 4.483±3.23 0.820±0.00 8.342±3.27 2.614±1.33 5.047±3.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XF CIL_0008XF_0001 VISTA 4:147181569-147782559
CIL_0008OE CIL_0008OE_0001 VISTA 4:147195167-147795934
CIL_0008H5 CIL_0008H5_0001 VISTA 4:147235170-147835800
CIL_00064D CIL_00064D_0002 CGP 4:147480917-147672044

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001569 IEA patterning of blood vessels
GO:0001666 IEA response to hypoxia
GO:0001701 IEA in utero embryonic development
GO:0001821 IEA histamine secretion
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0003094 IEA glomerular filtration
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004962 NAS endothelin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006939 NAS smooth muscle contraction
GO:0007165 TAS signal transduction
GO:0007186 NAS:IEA G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007202 TAS activation of phospholipase C activity
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007266 IEA Rho protein signal transduction
GO:0007507 IEA heart development
GO:0007568 IEA aging
GO:0007585 ISS respiratory gaseous exchange
GO:0008152 TAS metabolic process
GO:0008217 IEA regulation of blood pressure
GO:0008283 NAS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0014032 IEA neural crest cell development
GO:0014070 IEA response to organic cyclic compound
GO:0014824 IMP artery smooth muscle contraction
GO:0015758 ISS glucose transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030315 IEA T-tubule
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0031965 IEA nuclear membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0042310 IMP vasoconstriction
GO:0042482 IEA positive regulation of odontogenesis
GO:0043066 IEA negative regulation of apoptotic process
GO:0043084 IEA penile erection
GO:0043278 IEA response to morphine
GO:0045121 IEA membrane raft
GO:0048144 IEA fibroblast proliferation
GO:0048484 IEA enteric nervous system development
GO:0048659 IEA smooth muscle cell proliferation
GO:0050678 IEA regulation of epithelial cell proliferation
GO:0050729 IEA positive regulation of inflammatory response
GO:0051281 IEA positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051928 IEA positive regulation of calcium ion transport
GO:0060137 IEA maternal process involved in parturition
GO:0060322 IEA head development
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071260 IEA cellular response to mechanical stimulus
GO:0086100 IEA endothelin receptor signaling pathway
GO:0090023 IEA positive regulation of neutrophil chemotaxis
GO:0090184 IEA positive regulation of kidney development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034029 Ednra-001 protein_coding Mus_musculus 4e-22 111

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