C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sirtuin 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000328666 SIRT7-001 ENSG00000187531 9606 - 17:81911939-81918194 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000328666
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000328666 5.064±0.00 13.679±0.00 2.407±0.00 7.095±0.00 4.529±2.27 12.115±0.00 4.627±0.00 1.078±0.00 10.083±1.62 6.877±0.66 13.674±1.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LV CIL_0004LV_0001 CGP 17:81900965-81921323
CIL_0004LW CIL_0004LW_0001 CGP 17:81911939-81927714

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005730 IDA nucleolus
GO:0005731 IDA nucleolus organizer region
GO:0005737 IEA cytoplasm
GO:0007072 IMP positive regulation of transcription on exit from mitosis
GO:0009303 IMP rRNA transcription
GO:0046872 IEA metal ion binding
GO:0070403 IEA NAD+ binding
GO:0070932 IDA histone H3 deacetylation
GO:0070933 IDA histone H4 deacetylation
GO:0097372 IDA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000080202 Sirt7-001 protein_coding Mus_musculus 0 1380
ENSMUST00000134255 Sirt7-005 retained_intron Mus_musculus 0 1033
ENSMUST00000127882 Sirt7-006 retained_intron Mus_musculus 0 839
ENSMUST00000153532 Sirt7-008 retained_intron Mus_musculus 0 693
ENSMUST00000146809 Sirt7-003 protein_coding Mus_musculus 0 508
ENSMUST00000133625 Sirt7-011 retained_intron Mus_musculus 0 409

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