C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sirtuin 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080202 Sirt7-001 ENSMUSG00000025138 10090 - 11:120618372-120625014 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000080202
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000080202 19.889±0.36 23.632±0.00 21.618±3.27 16.855±1.97 25.101±3.08 7.964±0.00 25.857±2.13 23.369±3.24 27.701±2.51 25.225±4.12 19.806±0.00 5.725±1.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LV CIL_0004LV_0002 CGP 11:120610087-120625240
CIL_0004LW CIL_0004LW_0002 CGP 11:120618372-120633600

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003682 ISS chromatin binding
GO:0005515 IEA protein binding
GO:0005730 ISS nucleolus
GO:0005731 ISS nucleolus organizer region
GO:0005737 IEA cytoplasm
GO:0007072 ISS positive regulation of transcription on exit from mitosis
GO:0009303 ISS rRNA transcription
GO:0046872 IEA metal ion binding
GO:0070403 IEA NAD+ binding
GO:0070932 ISS histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 ISS NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000328666 SIRT7-001 protein_coding Homo_sapiens 0 1380
ENST00000536038 SIRT7-002 retained_intron Homo_sapiens 0 1035
ENST00000571233 SIRT7-021 retained_intron Homo_sapiens 0 372
ENST00000571832 SIRT7-004 retained_intron Homo_sapiens 0 693
ENST00000572350 SIRT7-017 retained_intron Homo_sapiens 0 713
ENST00000572902 SIRT7-008 protein_coding Homo_sapiens 0 918
ENST00000572976 SIRT7-006 retained_intron Homo_sapiens 0 409
ENST00000573367 SIRT7-015 retained_intron Homo_sapiens 0 196
ENST00000574153 SIRT7-023 retained_intron Homo_sapiens 0 202
ENST00000574495 SIRT7-009 retained_intron Homo_sapiens 0 289
ENST00000574992 SIRT7-007 retained_intron Homo_sapiens 0 486
ENST00000576156 SIRT7-022 retained_intron Homo_sapiens 0 372
ENST00000577065 SIRT7-018 retained_intron Homo_sapiens 0 584

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