C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000334220 DLST-001 ENSG00000119689 9606 + 14:74881893-74903745 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334220
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334220 4.017±0.00 4.531±0.00 7.774±0.00 1.021±0.00 3.293±1.62 7.214±0.00 8.431±1.75 10.200±0.00 2.932±0.25 2.713±0.00 3.220±0.00 14.753±7.34 21.329±4.47 3.810±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004KC CIL_0004KC_0002 CGP 14:74852871-74903745
CIL_0004K5 CIL_0004K5_0002 CGP 14:74881891-74923396

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004149 IEA dihydrolipoyllysine-residue succinyltransferase activity
GO:0005634 IDA nucleus
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006554 TAS lysine catabolic process
GO:0008152 IEA metabolic process
GO:0016020 IDA membrane
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0033512 IEA L-lysine catabolic process to acetyl-CoA via saccharopine
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045252 IEA oxoglutarate dehydrogenase complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053811 Dlst-201 protein_coding Mus_musculus 0 2063
ENSDART00000016614 dlst-001 protein_coding Danio_rerio 0 577
ENSDART00000135246 dlst-002 processed_transcript Danio_rerio 2.00386e-43 182
ENSDART00000145676 dlst-004 processed_transcript Danio_rerio 7e-19 100

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