C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenylate cyclase 2 (brain)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000338316 ADCY2-001 ENSG00000078295 9606 + 5:7396208-7830081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartENST00000338316
Transcript ID Brain Heart
ENST00000338316 4.018±0.63 0.052±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004016 ISS:IEA adenylate cyclase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005622 ISS intracellular
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 ISS cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0008179 ISS adenylate cyclase binding
GO:0008294 IEA calcium- and calmodulin-responsive adenylate cyclase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0030425 ISS dendrite
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0045121 ISS membrane raft
GO:0046872 IEA metal ion binding
GO:0046982 ISS protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022013 Adcy2-201 protein_coding Mus_musculus 0 4536
ENSDART00000046166 adcy2b-201 protein_coding Danio_rerio 0 584
ENSDART00000135348 adcy2b-001 protein_coding Danio_rerio 0 584

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