C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myocardin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343344 MYOCD-004 ENSG00000141052 9606 + 17:12666189-12763644 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YN CIL_0007YN_0001 VISTA 17:12172466-12773269
CIL_0008QC CIL_0008QC_0001 VISTA 17:12429509-13031929

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001076 ISS RNA polymerase II transcription factor binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001666 IEP response to hypoxia
GO:0003257 IDA positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0035051 NAS cardiocyte differentiation
GO:0035065 ISS regulation of histone acetylation
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045987 IDA positive regulation of smooth muscle contraction
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051145 IMP smooth muscle cell differentiation
GO:0051150 TAS regulation of smooth muscle cell differentiation
GO:0051152 IDA positive regulation of smooth muscle cell differentiation
GO:0055007 ISS cardiac muscle cell differentiation
GO:1900222 IMP negative regulation of beta-amyloid clearance
GO:2000721 IDA positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
GO:2000724 ISS positive regulation of cardiac vascular smooth muscle cell differentiation
GO:2000727 IDA positive regulation of cardiac muscle cell differentiation
GO:2001015 IDA negative regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102635 Myocd-001 protein_coding Mus_musculus 0 1550
ENSMUST00000108695 Myocd-201 protein_coding Mus_musculus 0 857
ENSMUST00000101042 Myocd-002 protein_coding Mus_musculus 0 845
ENSMUST00000144399 Myocd-005 protein_coding Mus_musculus 0 424

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