C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphofructokinase, liver
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000349048 PFKL-001 ENSG00000141959 9606 + 21:44300051-44327376 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000349048
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000349048 75.104±0.00 48.789±0.00 9.238±0.00 33.873±26.10 32.274±21.51 28.887±18.07 7.725±6.23 48.899±33.77 13.755±8.99 23.473±17.25 5.307±0.00 53.183±27.97 93.745±8.78 51.328±1.45

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003872 IDA:IEA 6-phosphofructokinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005945 IDA 6-phosphofructokinase complex
GO:0005975 TAS carbohydrate metabolic process
GO:0006002 IMP fructose 6-phosphate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006096 IEA glycolytic process
GO:0009749 IDA response to glucose
GO:0016020 IDA membrane
GO:0019900 IPI kinase binding
GO:0030388 IDA fructose 1,6-bisphosphate metabolic process
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0046676 IEA negative regulation of insulin secretion
GO:0046835 IEA carbohydrate phosphorylation
GO:0046872 IEA metal ion binding
GO:0048029 IEA monosaccharide binding
GO:0051259 IDA protein oligomerization
GO:0051289 IEA protein homotetramerization
GO:0070061 IDA fructose binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070095 IDA fructose-6-phosphate binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020522 Pfkl-001 protein_coding Mus_musculus 0 2706
ENSMUST00000149271 Pfkl-003 retained_intron Mus_musculus 0 366
ENSMUST00000148818 Pfkl-002 retained_intron Mus_musculus 0 233

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