C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP citrate lyase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000352035 ACLY-001 ENSG00000131473 9606 - 17:41866908-41918987 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000352035
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000352035 11.077±0.00 4.268±0.00 2.976±0.00 8.960±3.26 13.270±8.44 4.905±1.32 1.811±0.19 8.015±0.00 5.128±0.55 2.189±0.00 14.487±5.20 11.358±4.18 10.713±5.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000KS CIL_0000KS_0002 CGP 17:41853545-41930542
CIL_0006EG CIL_0006EG_0001 CGP 17:41866908-41965651

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003878 TAS:IEA ATP citrate synthase activity
GO:0004775 IEA succinate-CoA ligase (ADP-forming) activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA:IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006101 TAS citrate metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006200 TAS ATP catabolic process
GO:0008152 IEA metabolic process
GO:0008610 IDA lipid biosynthetic process
GO:0009346 TAS citrate lyase complex
GO:0015936 TAS coenzyme A metabolic process
GO:0016020 IDA membrane
GO:0019432 TAS triglyceride biosynthetic process
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0035338 TAS long-chain fatty-acyl-CoA biosynthetic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0046912 IEA transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
GO:0048037 IEA cofactor binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107389 Acly-005 protein_coding Mus_musculus 0 4793
ENSMUST00000007131 Acly-001 protein_coding Mus_musculus 0 2900
ENSMUST00000165111 Acly-201 protein_coding Mus_musculus 0 2896
ENSMUST00000107385 Acly-006 protein_coding Mus_musculus 0 1899
ENSDART00000156079 aclya-001 protein_coding Danio_rerio 0 1432
ENSDART00000044162 aclya-201 protein_coding Danio_rerio 0 1430
ENSMUST00000152969 Acly-003 processed_transcript Mus_musculus 0 885
ENSMUST00000154151 Acly-002 processed_transcript Mus_musculus 0 501
ENSMUST00000154888 Acly-004 processed_transcript Mus_musculus 0 361

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