C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sprouty-related, EVH1 domain containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000356388 SPRED2-001 ENSG00000198369 9606 - 2:65310851-65432177 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356388
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356388 22.068±0.00 4.294±0.00 0.334±0.00 3.268±1.78 5.447±0.00 3.905±2.53 2.811±2.43 4.877±2.63 2.407±0.72 5.774±5.25 1.918±1.01 5.335±2.03 7.411±1.93 3.774±2.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002N3 CIL_0002N3_0002 CGP 2:65227753-65432637

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0005173 ISS stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0009966 IEA regulation of signal transduction
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0030291 ISS protein serine/threonine kinase inhibitor activity
GO:0031410 IEA cytoplasmic vesicle
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 ISS regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093298 Spred2-201 protein_coding Mus_musculus 0 1604
ENSMUST00000093299 Spred2-001 protein_coding Mus_musculus 0 1079
ENSMUST00000121522 Gm14612-001 processed_pseudogene Mus_musculus 0 470
ENSMUST00000123036 Spred2-002 protein_coding Mus_musculus 0 396

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